Tosagestin

Tosagestin
Clinical data
Other namesORG-30659; Exogestin; Letogestin; 11-Methylene-δ15-norethisterone; 17α-Ethynyl-11-methylene-19-nor-δ15-testosterone
Routes of
administration		By mouth
Identifiers
  • (1S,2R,10R,11S,14R,15S)-14-ethynyl-14-hydroxy-15-methyl-17-methylidenetetracyclo[8.7.0.02,7.011,15]heptadeca-6,12-dien-5-one
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC21H24O2
Molar mass308.421 g·mol−1
3D model (JSmol)
  • CC12CC(=C)C3C(C1C=CC2(C#C)O)CCC4=CC(=O)CCC34
  • InChI=1S/C21H24O2/c1-4-21(23)10-9-18-17-7-5-14-11-15(22)6-8-16(14)19(17)13(2)12-20(18,21)3/h1,9-11,16-19,23H,2,5-8,12H2,3H3/t16-,17-,18-,19+,20-,21-/m0/s1
  • Key:YJSTYQGZKJHXLN-OLGWUGKESA-N

Tosagestin (INNTooltip International Nonproprietary Name, USANTooltip United States Adopted Name) (developmental code name ORG-30659), also known as 11-methylene-δ15-norethisterone or 17α-ethynyl-11-methylene-19-nor-δ15-testosterone, is a progestin of the 19-nortestosterone group which was under development by Organon in the United States and Europe as a hormonal contraceptive (in combination with ethinylestradiol) and for the treatment of menopausal symptoms but was never marketed.

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