Progesterone/hydroxyprogesterone heptanoate/α-tocopherol palmitate

< Progesterone < hydroxyprogesterone heptanoate
P4/OHPH/VE
Combination of
ProgesteroneProgestogen
Hydroxyprogesterone heptanoateProgestogen
α-Tocopherol palmitateVitamin E
Clinical data
Trade namesTocogestan
Other namesP4/OHPH/VE; P4/OHPH/α-TP
Routes of
administration		Intramuscular injection

Progesterone/hydroxyprogesterone heptanoate/α-tocopherol palmitate (P4/OHPH/VE), sold under the brand name Tocogestan, is a combination medication of progesterone (P4), a short-acting progestogen, hydroxyprogesterone heptanoate (OHPH), a long-acting progestogen, and α-tocopherol palmitate, a prodrug of α-tocopherol and form of vitamin E, which was previously used in France to support pregnancy in women but is no longer available. It contained 50 mg P4, 200 mg OHPH, and 250 mg in 2 mL oil solution, was provided in the form of 2 mL ampoules, and was administered by intramuscular injection.

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