Nifoxipam

Nifoxipam
Legal status
Legal status	AU: Unscheduled; BR: Class B1 (Psychoactive drugs); CA: Schedule IV; DE: NpSG (Industrial and scientific use only); UK: Under Psychoactive Substances Act; US: Unscheduled; UN: Unscheduled; In general legal for medical and research uses.;
Identifiers
	IUPAC name 5-(2-fluorophenyl)-3-hydroxy-7-nitro-2,3-dihydro-1H-1,4-benzodiazepin-2-one;
CAS Number	74723-10-7;
PubChem CID	3058221;
ChemSpider	2319383;
UNII	9O6C9M3CH6;
CompTox Dashboard (EPA)	DTXSID80996250 ;
Chemical and physical data
Formula	C15H10FN3O4
Molar mass	315.260 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C1C(O)N=C(C2=CC=CC=C2F)C3=CC([N+]([O-])=O)=CC=C3N1;
	InChI InChI=1S/C15H10FN3O4/c16-11-4-2-1-3-9(11)13-10-7-8(19(22)23)5-6-12(10)17-14(20)15(21)18-13/h1-7,15,21H,(H,17,20); Key:UHFIFTRHLBAWGY-UHFFFAOYSA-N;

Nifoxipam (3-hydroxydesmethylflunitrazepam, DP 370) is a benzodiazepine that is a minor metabolite of flunitrazepam and has been sold online as a designer drug.

Nifoxipam produces strong tranquillising and sleep-prolonging effects and has much lower toxicity compared to lormetazepam and flunitrazepam in mice.

Legal status


Legal status	AU: Unscheduled BR: Class B1 (Psychoactive drugs) CA: Schedule IV DE: NpSG (Industrial and scientific use only) UK: Under Psychoactive Substances Act US: Unscheduled UN: Unscheduled In general legal for medical and research uses.
Identifiers
IUPAC name 5-(2-fluorophenyl)-3-hydroxy-7-nitro-2,3-dihydro-1H-1,4-benzodiazepin-2-one
CAS Number	74723-10-7
PubChem CID	3058221
ChemSpider	2319383
UNII	9O6C9M3CH6
CompTox Dashboard (EPA)	DTXSID80996250
Chemical and physical data
Formula	C₁₅H₁₀FN₃O₄
Molar mass	315.260 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O=C1C(O)N=C(C2=CC=CC=C2F)C3=CC([N+]([O-])=O)=CC=C3N1
InChI InChI=1S/C15H10FN3O4/c16-11-4-2-1-3-9(11)13-10-7-8(19(22)23)5-6-12(10)17-14(20)15(21)18-13/h1-7,15,21H,(H,17,20) Key:UHFIFTRHLBAWGY-UHFFFAOYSA-N