YWHAB

YWHAB
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2BQ0, 2C23, 4DNK
Identifiers
Aliases	YWHAB, GW128, HEL-S-1, HS1, KCIP-1, YWHAA, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
External IDs	OMIM: 601289; MGI: 1891917; HomoloGene: 20724; GeneCards: YWHAB; OMA:YWHAB - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	44,908,532 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	163,860,508 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; Brodmann area 23; ; middle temporal gyrus; ; lateral nuclear group of thalamus; ; entorhinal cortex; ; parietal lobe; ; postcentral gyrus; ; Pons; ; pars compacta; ; superior frontal gyrus;
	Top expressed in
	substantia nigra; ; ventromedial nucleus; ; external carotid artery; ; internal carotid artery; ; motor neuron; ; saccule; ; facial motor nucleus; ; barrel cortex; ; anterior amygdaloid area; ; dorsomedial hypothalamic nucleus;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	transcription corepressor activity; protein domain specific binding; protein-containing complex binding; histone deacetylase binding; phosphoprotein binding; protein C-terminus binding; protein binding; enzyme binding; phosphoserine residue binding; cadherin binding; identical protein binding;
Cellular component	cytoplasm; membrane; focal adhesion; melanosome; transcription repressor complex; perinuclear region of cytoplasm; extracellular exosome; cytoplasmic vesicle membrane; nucleus; mitochondrion; cytosol; protein-containing complex; vacuole; vacuolar membrane;
Biological process	protein targeting; negative regulation of protein dephosphorylation; protein heterooligomerization; regulation of mRNA stability; positive regulation of catalytic activity; hippo signaling; cytoplasmic sequestering of protein; MAPK cascade; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; membrane organization; viral process; negative regulation of transcription, DNA-templated; negative regulation of G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	7529
	54401
	ENSG00000166913
	ENSMUSG00000018326
	P31946; Q4VY19
	Q9CQV8
	NM_139323; NM_003404
	NM_018753
	NP_003395; NP_647539
	NP_061223
	Wikidata
View/Edit Human	View/Edit Mouse

14-3-3 protein beta/alpha is a protein that in humans is encoded by the YWHAB gene.