William Howard Stein

William Howard Stein
Born(1911-06-25)June 25, 1911
New York City, New York, USA
DiedFebruary 2, 1980(1980-02-02) (aged 68)
New York City, New York, USA
EducationHarvard University
Columbia University
Spouse(s)Phoebe Hockstader (1936–1980; his death; 3 children) (1913–1989)
AwardsNobel Prize in Chemistry (1972)
Scientific career
FieldsBiochemistry
InstitutionsRockefeller University, University of Chicago
ThesisThe Composition of Elastin (1938)
Doctoral advisorHans Thacher Clarke

William Howard Stein (June 25, 1911 February 2, 1980) was an American biochemist who collaborated in the determination of the ribonuclease sequence, as well as how its structure relates to catalytic activity, earning a Nobel Prize in Chemistry in 1972 for his work. Stein was also involved in the invention of the automatic amino acid analyzer, an advancement in chromatography that opened the door to modern methods of chromatography, such as liquid chromatography and gas chromatography.