WWC1

WWC1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2Z0U
Identifiers
Aliases	WWC1, HBEBP3, HBEBP36, KIBRA, MEMRYQTL, PPP1R168, WW and C2 domain containing 1
External IDs	OMIM: 610533; MGI: 2388637; HomoloGene: 69180; GeneCards: WWC1; OMA:WWC1 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	168,472,303 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	35,871,354 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; parotid gland; ; buccal mucosa cell; ; renal medulla; ; caudate nucleus; ; putamen; ; kidney tubule; ; human kidney; ; nucleus accumbens; ; islet of Langerhans;
	Top expressed in
	vestibular membrane of cochlear duct; ; Epithelium of choroid plexus; ; lacrimal gland; ; choroid plexus of fourth ventricle; ; retinal pigment epithelium; ; right lung lobe; ; parotid gland; ; vestibular sensory epithelium; ; ciliary body; ; conjunctival fornix;
	More reference expression data
	n/a
Gene ontology
Molecular function	transcription coactivator activity; kinase binding; protein binding; molecular adaptor activity;
Cellular component	cytoplasm; cytosol; cell projection; membrane; plasma membrane; ruffle membrane; perinuclear region of cytoplasm; nucleus; protein-containing complex;
Biological process	regulation of transcription, DNA-templated; negative regulation of transcription by RNA polymerase II; hippo signaling; transcription, DNA-templated; negative regulation of hippo signaling; establishment of cell polarity; regulation of hippo signaling; negative regulation of organ growth; cell migration; positive regulation of MAPK cascade; regulation of intracellular transport; positive regulation of transcription of Notch receptor target;
	Sources:Amigo / QuickGO
Orthologs
	23286
	211652
	ENSG00000113645
	ENSMUSG00000018849
	Q8IX03
	Q5SXA9
	NM_001161661; NM_001161662; NM_015238
	NM_170779
	NP_001155133; NP_001155134; NP_056053
	NP_740749
	Wikidata
View/Edit Human	View/Edit Mouse

Protein KIBRA also known as kidney and brain expressed protein (KIBRA) or WW domain-containing protein 1 (WWC1) is a protein that in humans is encoded by the WWC1 gene.