USP5

USP5
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2DAG, 2DAK, 2G43, 2G45, 3IHP
Identifiers
Aliases	USP5, ISOT, ubiquitin specific peptidase 5
External IDs	OMIM: 601447; MGI: 1347343; HomoloGene: 55758; GeneCards: USP5; OMA:USP5 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	6,866,632 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	124,806,447 bp
RNA expression pattern
	Top expressed in
	prefrontal cortex; ; left testis; ; right testis; ; right frontal lobe; ; right adrenal gland; ; right adrenal cortex; ; Brodmann area 9; ; left adrenal gland; ; lateral nuclear group of thalamus; ; gastrocnemius muscle;
	Top expressed in
	spermatocyte; ; dentate gyrus of hippocampal formation granule cell; ; superior frontal gyrus; ; primary visual cortex; ; perirhinal cortex; ; entorhinal cortex; ; ventricular zone; ; otic vesicle; ; lip; ; Medulla Oblongata;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	peptidase activity; cysteine-type peptidase activity; cysteine-type endopeptidase activity; zinc ion binding; ubiquitin binding; protein binding; hydrolase activity; metal ion binding; thiol-dependent deubiquitinase;
Cellular component	lysosome; cytosol;
Biological process	protein K48-linked deubiquitination; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ubiquitin-dependent protein catabolic process; proteolysis; protein deubiquitination; protein ubiquitination;
	Sources:Amigo / QuickGO
Orthologs
	8078
	22225
	ENSG00000111667
	ENSMUSG00000038429
	P45974
	P56399
	NM_001098536; NM_003481
	NM_013700; NM_001326594
NP_001092006; NP_003472; NP_001369517; NP_001369518; NP_001369519;
	NP_001369520
	NP_001313523; NP_038728
	Wikidata
View/Edit Human	View/Edit Mouse

Ubiquitin specific peptidase 5 is an enzyme that in humans is encoded by the USP5 gene.