UQCRC1

UQCRC1
Identifiers
Aliases	UQCRC1, D3S3191, QCR1, UQCR1, ubiquinol-cytochrome c reductase core protein I, ubiquinol-cytochrome c reductase core protein 1, PKNPY
External IDs	OMIM: 191328; MGI: 107876; HomoloGene: 2525; GeneCards: UQCRC1; OMA:UQCRC1 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	48,610,976 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	108,778,691 bp
RNA expression pattern
	Top expressed in
	apex of heart; ; left ventricle; ; right ventricle; ; triceps brachii muscle; ; myocardium of left ventricle; ; gastrocnemius muscle; ; muscle of thigh; ; mucosa of transverse colon; ; right auricle of heart; ; vastus lateralis muscle;
	Top expressed in
	proximal tubule; ; heart; ; right kidney; ; muscle tissue; ; muscle of thigh; ; skeletal muscle tissue; ; quadriceps femoris muscle; ; human kidney; ; neural layer of retina; ; duodenum;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	ubiquinol-cytochrome-c reductase activity; protein-containing complex binding; zinc ion binding; metal ion binding; catalytic activity; metalloendopeptidase activity; ubiquitin protein ligase binding;
Cellular component	mitochondrial respiratory chain complex III; membrane; myelin sheath; mitochondrion; mitochondrial respirasome; mitochondrial inner membrane; respirasome; cytosol;
Biological process	protein processing; response to activity; aerobic respiration; oxidative phosphorylation; response to alkaloid; mitochondrial electron transport, ubiquinol to cytochrome c; proton transmembrane transport; proteolysis;
	Sources:Amigo / QuickGO
Orthologs
	7384
	22273
	ENSG00000010256
	ENSMUSG00000025651
	P31930
	Q9CZ13
	NM_003365
	NM_025407
	NP_003356
	NP_079683
	Wikidata
View/Edit Human	View/Edit Mouse

Cytochrome b-c1 complex subunit 1, mitochondrial is a protein that in humans is encoded by the UQCRC1 gene.

Its gene product is a subunit of the respiratory chain protein Ubiquinol Cytochrome c Reductase (UQCR, Complex III or Cytochrome bc1 complex), which consists of the products of one mitochondrially encoded gene, MTCYTB (mitochondrial cytochrome b) and ten nuclear genes: UQCRC1, UQCRC2, Cytochrome c1, UQCRFS1 (Rieske protein), UQCRB, "11kDa protein", UQCRH (cyt c1 Hinge protein), Rieske Protein presequence, "cyt. c1 associated protein", and Rieske-associated protein.