Ubiquitin D

UBD
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2MBE
Identifiers
Aliases	UBD, FAT10, GABBR1, UBD-3, ubiquitin D
External IDs	OMIM: 606050; MGI: 1344410; HomoloGene: 4665; GeneCards: UBD; OMA:UBD - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	29,559,732 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	37,506,986 bp
RNA expression pattern
	Top expressed in
	appendix; ; lymph node; ; islet of Langerhans; ; rectum; ; gallbladder; ; human kidney; ; tonsil; ; olfactory zone of nasal mucosa; ; liver; ; spleen;
	Top expressed in
	thymus; ; mesenteric lymph nodes; ; jejunum; ; mucous cell of stomach; ; lactiferous gland; ; subcutaneous adipose tissue; ; embryo; ; duodenum; ; spleen; ; intestinal villus;
	More reference expression data
	n/a
Gene ontology
Molecular function	proteasome binding; protein binding;
Cellular component	cytoplasm; aggresome; nucleus; fibrillar center; cytosol;
Biological process	positive regulation of I-kappaB kinase/NF-kappaB signaling; response to tumor necrosis factor; myeloid dendritic cell differentiation; protein modification by small protein conjugation; protein ubiquitination; ubiquitin-dependent protein catabolic process; response to interferon-gamma; proteolysis; aggresome assembly; positive regulation of apoptotic process; post-translational protein modification; regulation of mitotic cell cycle phase transition;
	Sources:Amigo / QuickGO
Orthologs
	10537
	24108
ENSG00000228913; ENSG00000231968; ENSG00000206468; ENSG00000206513; ENSG00000224654;
	ENSG00000213886; ENSG00000226898
	ENSMUSG00000035186
	O15205
	P63072
	NM_006398
	NM_023137
	NP_006389
	NP_075626
	Wikidata
View/Edit Human	View/Edit Mouse

Ubiquitin D is a protein that in humans is encoded by the UBD gene, also known as FAT10. UBD acts like ubiquitin, by covalently modifying proteins and tagging them for destruction in the proteasome.