U.S. Route 52 in South Carolina

U.S. Highway 52
U.S. Highway 52
	US 52 highlighted in red
Route information
	Maintained by SCDOT
Length	159.960 mi (257.431 km)
Existed	1935–present
Major junctions
East end	Line Street / Meeting Street in Charleston
	I-26 / US 17 in Charleston; US 78 in North Charleston; I-526 in North Charleston; ; US 17 Alt. in Moncks Corner; US 521 near Greeleyville; US 378 in Lake City; US 301 / SC 327 in Effingham; US 76 in Florence; I-95 in Florence; US 1 / SC 9 in Cheraw;
West end	US 52 at the North Carolina line near Cheraw
Location
Country	United States
State	South Carolina
Counties	Charleston, Berkeley, Williamsburg, Florence, Darlington, Chesterfield
Highway system
	United States Numbered Highway System; List; Special; Divided; South Carolina State Highway System; Interstate; US; State; Scenic;

U.S. Route 52 (US 52) is an east–west United States Numbered Highway that runs for 159.960-mile (257.431 km) from Charleston to the North Carolina state line near Cheraw. It serves as a strategic highway through the central part of the state.