Topiroxostat

Topiroxostat
Clinical data
Trade namesTopiloric, Uriadec
ATC code
  • None
Legal status
Legal status
  • Approved in Japan
Identifiers
  • 4-[5-(4-Pyridinyl)-1H-1,2,4-triazol-3-yl]-2-pyridinecarbonitrile
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC13H8N6
Molar mass248.249 g·mol−1
3D model (JSmol)
  • C1=CN=CC=C1C2=NC(=NN2)C3=CC(=NC=C3)C#N
  • InChI=1S/C13H8N6/c14-8-11-7-10(3-6-16-11)13-17-12(18-19-13)9-1-4-15-5-2-9/h1-7H,(H,17,18,19)
  • Key:UBVZQGOVTLIHLH-UHFFFAOYSA-N

Topiroxostat (INN; trade names Topiloric, Uriadec) is a drug for the treatment of gout and hyperuricemia. It was approved for use in Japan in June 2013.

Topiroxostat is a xanthine oxidase inhibitor which reduces serum urate levels.