Thozalinone

Thozalinone
Clinical data
Other names	Tozalinone, Thozalinon
Routes of; administration	Oral
ATC code	none;
Legal status
Legal status	In general: ℞ (Prescription only);
Identifiers
	IUPAC name (RS)-2-(Dimethylamino)-5-phenyl-1,3-oxazol-4(5H)-one;
CAS Number	655-05-0 ;
PubChem CID	12602;
ChemSpider	12082 ;
UNII	68X5932947;
KEGG	D06115 ;
ChEMBL	ChEMBL2105457;
CompTox Dashboard (EPA)	DTXSID70862359 ;
Chemical and physical data
Formula	C11H12N2O2
Molar mass	204.229 g·mol−1
3D model (JSmol)	Interactive image;
Chirality	Racemic mixture
	SMILES O=C2\N=C(/OC2c1ccccc1)N(C)C;
	InChI InChI=1S/C11H12N2O2/c1-13(2)11-12-10(14)9(15-11)8-6-4-3-5-7-8/h3-7,9H,1-2H3 ; Key:JJSHYECKYLDYAR-UHFFFAOYSA-N ;
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Thozalinone (USAN) (brand name Stimsen; former developmental code name CL-39808) is a psychostimulant that has been used as an antidepressant in Europe. It has also been trialed as an anorectic. Thozalinone is described as a "dopaminergic stimulant", and likely acts via inducing the release of dopamine and to a minimal extent norepinephrine; similar to analogue pemoline, it is reportedly devoid of abuse potential unlike other dopaminergic psychostimulants.

Clinical data


Other names	Tozalinone, Thozalinon
Routes of administration	Oral
ATC code	none
Legal status
Legal status	In general: ℞ (Prescription only)
Identifiers
IUPAC name (RS)-2-(Dimethylamino)-5-phenyl-1,3-oxazol-4(5H)-one
CAS Number	655-05-0^N
PubChem CID	12602
ChemSpider	12082^Y
UNII	68X5932947
KEGG	D06115^Y
ChEMBL	ChEMBL2105457
CompTox Dashboard (EPA)	DTXSID70862359
Chemical and physical data
Formula	C₁₁H₁₂N₂O₂
Molar mass	204.229 g·mol⁻¹
3D model (JSmol)	Interactive image
Chirality	Racemic mixture
SMILES O=C2\N=C(/OC2c1ccccc1)N(C)C
InChI InChI=1S/C11H12N2O2/c1-13(2)11-12-10(14)9(15-11)8-6-4-3-5-7-8/h3-7,9H,1-2H3^Y Key:JJSHYECKYLDYAR-UHFFFAOYSA-N^Y
^NY (what is this?) (verify)