TUSC2

TUSC2
Identifiers
Aliases	TUSC2, C3orf11, FUS1, PAP, PDAP2, tumor suppressor candidate 2, tumor suppressor 2, mitochondrial calcium regulator
External IDs	OMIM: 607052; MGI: 1931086; HomoloGene: 5264; GeneCards: TUSC2; OMA:TUSC2 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	50,328,251 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	107,443,311 bp
RNA expression pattern
	Top expressed in
	prefrontal cortex; ; cingulate gyrus; ; anterior cingulate cortex; ; right frontal lobe; ; Brodmann area 9; ; pars compacta; ; pars reticulata; ; nucleus accumbens; ; Amygdala; ; lateral nuclear group of thalamus;
	Top expressed in
	right kidney; ; superior frontal gyrus; ; muscle of thigh; ; primary visual cortex; ; dentate gyrus of hippocampal formation granule cell; ; gastrula; ; proximal tubule; ; neural layer of retina; ; cerebellar cortex; ; neural tube;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	mitochondrion;
Biological process	regulation of mitochondrial membrane potential; cell-cell signaling; cell cycle; chemokine (C-C motif) ligand 5 production; cell population proliferation; inflammatory response; negative regulation of interleukin-17 production; cell maturation; neutrophil-mediated killing of gram-negative bacterium; regulation of reactive oxygen species metabolic process; defense response to Gram-negative bacterium; interleukin-15 production; positive regulation of interleukin-10 production; phagocytosis; natural killer cell differentiation;
	Sources:Amigo / QuickGO
Orthologs
	11334
	80385
	ENSG00000114383
	ENSMUSG00000010054
	O75896
	Q9WVF8
	NM_007275
	NM_019742
	NP_009206
	NP_062716
	Wikidata
View/Edit Human	View/Edit Mouse

Tumor suppressor candidate 2 is a protein that in humans is encoded by the TUSC2 gene.

This gene is a highly conserved lung cancer candidate gene. No other information about this gene is currently available.