Tubulin alpha-1A chain

TUBA1A
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3HKC, 4X20, 3HKE, 3N2G, 4X1Y, 3N2K, 4X1I, 4X1K, 3HKB, 3HKD, 5JCO
Identifiers
Aliases	TUBA1A, B-ALPHA-1, LIS3, TUBA3, tubulin alpha 1a
External IDs	OMIM: 602529; MGI: 98869; HomoloGene: 68498; GeneCards: TUBA1A; OMA:TUBA1A - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	49,189,080 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	98,851,584 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; ganglionic eminence; ; inferior ganglion of vagus nerve; ; superior vestibular nucleus; ; spinal ganglia; ; inferior olivary nucleus; ; ventricular zone; ; bronchial epithelial cell; ; optic nerve; ; subthalamic nucleus;
	Top expressed in
	trigeminal ganglion; ; mammillary body; ; medial dorsal nucleus; ; fossa; ; condyle; ; medial vestibular nucleus; ; median eminence; ; superior cervical ganglion; ; medial geniculate nucleus; ; paraventricular nucleus of hypothalamus;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; protein domain specific binding; GTP binding; structural molecule activity; structural constituent of cytoskeleton; protein binding; GTPase activity;
Cellular component	cytoplasm; recycling endosome; cytosol; myelin sheath; cytoplasmic microtubule; cytoplasmic ribonucleoprotein granule; microtubule; extracellular exosome; cytoskeleton; nucleus; microtubule cytoskeleton; membrane raft; neuromuscular junction;
Biological process	cytoskeleton-dependent intracellular transport; cell division; G2/M transition of mitotic cell cycle; microtubule-based process; cytoskeleton organization; ciliary basal body-plasma membrane docking; regulation of G2/M transition of mitotic cell cycle; microtubule cytoskeleton organization; mitotic cell cycle; regulation of synapse organization;
	Sources:Amigo / QuickGO
Orthologs
	7846
	22142
	ENSG00000167552
	ENSMUSG00000072235
	Q71U36
	P68369
	NM_006009; NM_001270399; NM_001270400
	NM_011653
	NP_001257328; NP_001257329; NP_006000
	NP_035783
	Wikidata
View/Edit Human	View/Edit Mouse

Tubulin alpha-1A chain is a protein that in humans is encoded by the TUBA1A gene.

Tubulin alpha-1A chain is a type of alpha-tubulin involved in the formation of microtubules, which are structural proteins that play a role in the cytoskeletal structure. Microtubules are composed of heterodimers of alpha- and beta-tubulin molecules. Tubulin alpha-1A (TUBA1A) is a primary alpha-tubulin expressed in the human fetal brain, specifically found in that structure.