Transformation/transcription domain-associated protein

TRRAP
Identifiers
Aliases	TRRAP, PAF350/400, PAF400, STAF40, TR-AP, Tra1, transformation/transcription domain associated protein, DEDDFA, DFNA75
External IDs	OMIM: 603015; MGI: 2153272; HomoloGene: 39246; GeneCards: TRRAP; OMA:TRRAP - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	99,050,831 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	144,796,588 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; sural nerve; ; ganglionic eminence; ; anterior pituitary; ; buccal mucosa cell; ; skin of thigh; ; testicle; ; stromal cell of endometrium; ; right hemisphere of cerebellum; ; granulocyte;
	Top expressed in
	yolk sac; ; Rostral migratory stream; ; ventricular zone; ; internal carotid artery; ; neural layer of retina; ; anterior amygdaloid area; ; stroma of bone marrow; ; maxillary prominence; ; mandibular prominence; ; nucleus accumbens;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	transcription coregulator activity; protein binding; thiol-dependent deubiquitinase; kinase activity;
Cellular component	Golgi apparatus; transcription factor TFTC complex; NuA4 histone acetyltransferase complex; nucleoplasm; nucleus; Swr1 complex; histone acetyltransferase complex; SAGA complex;
Biological process	regulation of transcription, DNA-templated; histone H2A acetylation; transcription, DNA-templated; histone deubiquitination; histone H4 acetylation; phosphorylation; beta-catenin-TCF complex assembly; histone acetylation; protein deubiquitination; DNA repair; chromatin organization;
	Sources:Amigo / QuickGO
Orthologs
	8295
	100683
	ENSG00000196367
	ENSMUSG00000045482
	Q9Y4A5
	Q80YV3
	NM_003496; NM_001244580; NM_001375524
	NM_001081362; NM_133901
	NP_001231509; NP_003487; NP_001362453
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Transformation/transcription domain-associated protein, also known as TRRAP, is a protein that in humans is encoded by the TRRAP gene. TRRAP belongs to the phosphatidylinositol 3-kinase-related kinase protein family.