TRIM33

TRIM33
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3U5M, 3U5N, 3U5O, 3U5P
Identifiers
Aliases	TRIM33, ECTO, PTC7, RFG7, TF1G, TIF1G, TIF1GAMMA, TIFGAMMA, tripartite motif containing 33
External IDs	OMIM: 605769; MGI: 2137357; HomoloGene: 9296; GeneCards: TRIM33; OMA:TRIM33 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	114,511,203 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	103,266,091 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; Epithelium of choroid plexus; ; Brodmann area 23; ; corpus epididymis; ; nipple; ; cerebellar vermis; ; tibia; ; Region I of hippocampus proper; ; epithelium of nasopharynx; ; seminal vesicula;
	Top expressed in
	genital tubercle; ; primitive streak; ; tail of embryo; ; ciliary body; ; zygote; ; trigeminal ganglion; ; iris; ; Epithelium of choroid plexus; ; retinal pigment epithelium; ; secondary oocyte;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	DNA binding; R-SMAD binding; co-SMAD binding; zinc ion binding; metal ion binding; ubiquitin-protein transferase activity; protein binding; transferase activity;
Cellular component	intracellular anatomical structure; nucleus; nucleoplasm;
Biological process	regulation of transcription, DNA-templated; negative regulation of transcription by RNA polymerase II; regulation of transforming growth factor beta receptor signaling pathway; negative regulation of BMP signaling pathway; protein ubiquitination; negative regulation of transcription, DNA-templated; transcription, DNA-templated;
	Sources:Amigo / QuickGO
Orthologs
	51592
	94093
	ENSG00000197323
	ENSMUSG00000033014
	Q9UPN9
	Q99PP7
	NM_015906; NM_033020
	NM_001079830; NM_053170
	NP_056990; NP_148980
	NP_001073299; NP_444400
	Wikidata
View/Edit Human	View/Edit Mouse

E3 ubiquitin-protein ligase TRIM33, also known as (ectodermin homolog and tripartite motif-containing 33) is a protein encoded in the human by the gene TRIM33, a member of the tripartite motif family.

TRIM33 is thought to be a transcriptional corepressor. However unlike the related TRIM24 and TRIM28 proteins, few transcription factors such as SMAD4 that interact with TRIM33 have been identified.