TRIM32

TRIM32
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2CT2, 5FEY
Identifiers
Aliases	TRIM32, BBS11, HT2A, LGMD2H, TATIP, tripartite motif containing 32, LGMDR8
External IDs	OMIM: 602290; MGI: 1917057; HomoloGene: 36327; GeneCards: TRIM32; OMA:TRIM32 - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	116,701,300 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	65,534,475 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; tibialis anterior muscle; ; gastrocnemius muscle; ; secondary oocyte; ; testicle; ; muscle of thigh; ; deltoid muscle; ; gonad; ; Skeletal muscle tissue of biceps brachii; ; bronchial epithelial cell;
	Top expressed in
	dorsomedial hypothalamic nucleus; ; piriform cortex; ; habenula; ; ventral tegmental area; ; superior colliculus; ; subiculum; ; visual cortex; ; dorsal tegmental nucleus; ; medial geniculate nucleus; ; lobe of cerebellum;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	ubiquitin protein ligase activity; myosin binding; transcription coactivator activity; zinc ion binding; Tat protein binding; metal ion binding; ubiquitin-protein transferase activity; protein self-association; ubiquitin binding; protein binding; RNA binding; translation initiation factor binding; transferase activity; identical protein binding;
Cellular component	cytoplasm; cytosol; intracellular anatomical structure; striated muscle myosin thick filament; nucleus;
Biological process	positive regulation of interleukin-17-mediated signaling pathway; axon development; positive regulation of cell motility; positive regulation of protein catabolic process; muscle cell cellular homeostasis; positive regulation of tumor necrosis factor-mediated signaling pathway; positive regulation of cell migration; positive regulation of DNA-binding transcription factor activity; protein polyubiquitination; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage; actin ubiquitination; regulation of type I interferon production; response to tumor necrosis factor; positive regulation of neurogenesis; positive regulation of cell growth; positive regulation of cell cycle; positive regulation of NF-kappaB transcription factor activity; protein ubiquitination; positive regulation of neuron differentiation; tissue homeostasis; positive regulation of striated muscle cell differentiation; positive regulation of proteolysis; positive regulation of I-kappaB kinase/NF-kappaB signaling; innate immune response; negative regulation of fibroblast proliferation; positive regulation of chemokine (C-C motif) ligand 20 production; fat cell differentiation; response to UV; negative regulation of viral transcription; ubiquitin-dependent protein catabolic process; positive regulation of nucleic acid-templated transcription; protein K48-linked ubiquitination;
	Sources:Amigo / QuickGO
Orthologs
	22954
	69807
	ENSG00000119401
	ENSMUSG00000051675
	Q13049
	Q8CH72
	NM_001099679; NM_012210; NM_001379048; NM_001379049; NM_001379050
	NM_001161782; NM_053084
	NP_001093149; NP_036342; NP_001365977; NP_001365978; NP_001365979
	NP_001155254; NP_444314
	Wikidata
View/Edit Human	View/Edit Mouse

Tripartite motif-containing protein 32 is a protein that in humans is encoded by the TRIM32 gene. Since its discovery in 1995, TRIM32 has been shown to be implicated in a number of diverse biological pathways.