TRAT1

TRAT1
Identifiers
Aliases	TRAT1, TCRIM, TRIM, HSPC062, pp29/30, T cell receptor associated transmembrane adaptor 1, T-cell receptor associated transmembrane adaptor 1
External IDs	OMIM: 604962; MGI: 1924897; HomoloGene: 41130; GeneCards: TRAT1; OMA:TRAT1 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	108,855,005 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	48,592,384 bp
RNA expression pattern
	Top expressed in
	thymus; ; buccal mucosa cell; ; lymph node; ; testicle; ; blood; ; granulocyte; ; appendix; ; epithelium of nasopharynx; ; spleen; ; epithelium of colon;
	Top expressed in
	thymus; ; blood; ; mesenteric lymph nodes; ; embryo; ; spleen; ; subcutaneous adipose tissue; ; superior frontal gyrus; ; gastrula; ; primary visual cortex; ; vastus lateralis muscle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transmembrane receptor protein tyrosine kinase adaptor activity; phosphatidylinositol-4,5-bisphosphate 3-kinase activity;
Cellular component	integral component of membrane; membrane; plasma membrane; integral component of plasma membrane; T cell receptor complex;
Biological process	positive regulation of calcium-mediated signaling; adaptive immune response; immune system process; positive regulation of T cell receptor signaling pathway; negative regulation of transport; cellular defense response; T cell receptor signaling pathway; negative regulation of receptor recycling; signal transduction; phosphatidylinositol phosphate biosynthetic process; transmembrane receptor protein tyrosine kinase signaling pathway; positive regulation of protein kinase B signaling;
	Sources:Amigo / QuickGO
Orthologs
	50852
	77647
	ENSG00000163519
	ENSMUSG00000030775
	Q6PIZ9
	Q3UU67
	NM_016388; NM_001317747
	NM_198297
	NP_001304676; NP_057472
	NP_938039
	Wikidata
View/Edit Human	View/Edit Mouse

T-cell receptor-associated transmembrane adapter 1 is a protein that in humans is encoded by the TRAT1 gene.