TOB1

TOB1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2D5R, 2Z15, 5CI8, 5CI9
Identifiers
Aliases	TOB1, APRO6, PIG49, TOB, TROB, TROB1, transducer of ERBB2, 1, APRO5
External IDs	OMIM: 605523; MGI: 1349721; HomoloGene: 31334; GeneCards: TOB1; OMA:TOB1 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	50,867,978 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	94,106,321 bp
RNA expression pattern
	Top expressed in
	mucosa of paranasal sinus; ; germinal epithelium; ; skin of thigh; ; Skeletal muscle tissue of biceps brachii; ; seminal vesicula; ; Epithelium of choroid plexus; ; trachea; ; vastus lateralis muscle; ; cardia; ; Skeletal muscle tissue of rectus abdominis;
	Top expressed in
	extensor digitorum longus muscle; ; plantaris muscle; ; pineal gland; ; submandibular gland; ; parotid gland; ; seminal vesicula; ; intercostal muscle; ; triceps brachii muscle; ; digastric muscle; ; sternocleidomastoid muscle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	receptor tyrosine kinase binding; SMAD binding; protein binding; transcription corepressor activity;
Cellular component	CCR4-NOT complex; cytoplasm; nucleus;
Biological process	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; negative regulation of osteoblast differentiation; negative regulation of nuclear-transcribed mRNA poly(A) tail shortening; negative regulation of nucleic acid-templated transcription; negative regulation of BMP signaling pathway; negative regulation of translation; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening; BMP signaling pathway; negative regulation of cell population proliferation; positive regulation of signal transduction; regulation of SMAD protein signal transduction; regulation of gene expression;
	Sources:Amigo / QuickGO
Orthologs
	10140
	22057
	ENSG00000141232
	ENSMUSG00000037573
	P50616
	Q61471
	NM_005749; NM_001243877; NM_001243885
	NM_009427
	NP_001230806; NP_001230814; NP_005740
	NP_033453
	Wikidata
View/Edit Human	View/Edit Mouse

Protein Tob1 is a protein that in humans is encoded by the TOB1 gene.