TNFAIP1

TNFAIP1
Identifiers
Aliases	TNFAIP1, B12, B61, BTBD34, EDP1, hBACURD2, TNF alpha induced protein 1
External IDs	OMIM: 191161; MGI: 104961; HomoloGene: 22519; GeneCards: TNFAIP1; OMA:TNFAIP1 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	28,347,009 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	78,427,158 bp
RNA expression pattern
	Top expressed in
	hair follicle; ; spleen; ; upper lobe of left lung; ; left ventricle; ; right lobe of liver; ; gallbladder; ; right lung; ; islet of Langerhans; ; body of pancreas; ; smooth muscle tissue;
	Top expressed in
	Paneth cell; ; endocardial cushion; ; endothelial cell of lymphatic vessel; ; fossa; ; condyle; ; ciliary body; ; medullary collecting duct; ; retinal pigment epithelium; ; atrioventricular junction; ; internal carotid artery;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	ubiquitin-protein transferase activity; protein binding; protein domain specific binding; identical protein binding;
Cellular component	cytoplasm; endosome; Cul3-RING ubiquitin ligase complex; nucleolus; nucleus;
Biological process	positive regulation of DNA replication; DNA replication; negative regulation of Rho protein signal transduction; protein homooligomerization; cell migration; protein ubiquitination; immune response; stress fiber assembly; proteasome-mediated ubiquitin-dependent protein catabolic process; apoptotic process;
	Sources:Amigo / QuickGO
Orthologs
	7126
	21927
	ENSG00000109079
	ENSMUSG00000017615
	Q13829
	O70479
	NM_021137
	NM_001159392; NM_009395
	NP_066960
	NP_001152864; NP_033421
	Wikidata
View/Edit Human	View/Edit Mouse

BTB/POZ domain-containing protein TNFAIP1 is a protein that in humans is encoded by the TNFAIP1 gene.

This gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. Studies of a similar gene in mouse suggest that the expression of this gene is developmentally regulated in a tissue-specific manner.