TLE2

TLE2
Identifiers
Aliases	TLE2, ESG, ESG2, GRG2, transducin like enhancer of split 2, TLE family member 2, transcriptional corepressor
External IDs	OMIM: 601041; MGI: 104635; HomoloGene: 20693; GeneCards: TLE2; OMA:TLE2 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	3,047,635 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	81,426,679 bp
RNA expression pattern
	Top expressed in
	cerebellar hemisphere; ; right hemisphere of cerebellum; ; cerebellar vermis; ; tibial nerve; ; right lobe of thyroid gland; ; left lobe of thyroid gland; ; left uterine tube; ; parotid gland; ; apex of heart; ; sural nerve;
	Top expressed in
	cerebellar cortex; ; neural layer of retina; ; medullary collecting duct; ; lobe of cerebellum; ; cerebellar vermis; ; primary visual cortex; ; internal carotid artery; ; adrenal gland; ; superior frontal gyrus; ; molar;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; transcription corepressor activity;
Cellular component	nucleus; focal adhesion; nucleoplasm; extracellular space; nuclear body; transcription regulator complex;
Biological process	animal organ morphogenesis; negative regulation of transcription, DNA-templated; regulation of transcription, DNA-templated; Wnt signaling pathway; negative regulation of canonical Wnt signaling pathway; transcription, DNA-templated; signal transduction; beta-catenin-TCF complex assembly;
	Sources:Amigo / QuickGO
Orthologs
	7089
	21886
	ENSG00000065717
	ENSMUSG00000034771
	Q04725
	Q9WVB2
	NM_001144761; NM_001144762; NM_001300846; NM_003260
	NM_001252401; NM_019725
	NP_001138233; NP_001138234; NP_001287775; NP_003251
	NP_001239330; NP_062699
	Wikidata
View/Edit Human	View/Edit Mouse

Transducin-like enhancer protein 2 is a protein that in humans is encoded by the TLE2 gene.