THOC2

THOC2
Identifiers
Aliases	THOC2, CXorf3, THO2, dJ506G2.1, hTREX120, MRX12, MRX35, THO complex 2
External IDs	OMIM: 300395; MGI: 2442413; HomoloGene: 69669; GeneCards: THOC2; OMA:THOC2 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	123,733,056 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	41,009,551 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; Achilles tendon; ; sural nerve; ; ventricular zone; ; epithelium of colon; ; right lung; ; visceral pleura; ; left ovary; ; gastric mucosa; ; body of pancreas;
	Top expressed in
	Rostral migratory stream; ; sciatic nerve; ; retinal pigment epithelium; ; primitive streak; ; ciliary body; ; tail of embryo; ; medullary collecting duct; ; umbilical cord; ; vestibular membrane of cochlear duct; ; median eminence;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; RNA binding; mRNA binding;
Cellular component	THO complex; nuclear speck; THO complex part of transcription export complex; transcription export complex; nucleus; nucleoplasm;
Biological process	poly(A)+ mRNA export from nucleus; mRNA processing; mRNA transport; neuron development; viral mRNA export from host cell nucleus; RNA splicing; generation of neurons; RNA export from nucleus; mRNA export from nucleus; mRNA 3'-end processing; cell morphogenesis; blastocyst development; regulation of gene expression; regulation of mRNA export from nucleus; negative regulation of neuron projection development; stem cell division;
	Sources:Amigo / QuickGO
Orthologs
	57187
	331401
	ENSG00000125676
	ENSMUSG00000037475
	Q8NI27
	B1AZI6
	NM_001081550; NM_020449
	NM_001033422
	NP_001075019
	NP_001028594
	Wikidata
View/Edit Human	View/Edit Mouse

THO complex subunit 2 is a protein that in humans is encoded by the THOC2 gene.

THO2 is part of the TREX (transcription/export) complex, which includes TEX1 (MIM 606929), HPR1 (MIM 606930), ALY (MIM 604171), and UAP56 (MIM 606390).[supplied by OMIM]