TARBP2

TARBP2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2CPN, 3ADL, 3LLH, 4WYQ
Identifiers
Aliases	TARBP2, LOQS, TRBP, TRBP1, TRBP2, RISC loading complex RNA binding subunit, TARBP2 subunit of RISC loading complex
External IDs	OMIM: 605053; MGI: 103027; HomoloGene: 7562; GeneCards: TARBP2; OMA:TARBP2 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	53,506,431 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	102,432,111 bp
RNA expression pattern
	Top expressed in
	right hemisphere of cerebellum; ; right uterine tube; ; right lobe of thyroid gland; ; right adrenal gland; ; right adrenal cortex; ; mucosa of transverse colon; ; granulocyte; ; left lobe of thyroid gland; ; right lobe of liver; ; body of pancreas;
	Top expressed in
	spermatocyte; ; yolk sac; ; testicle; ; spermatid; ; epiblast; ; embryo; ; Mesencephalon; ; neural tube; ; heart; ; embryo;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein N-terminus binding; protein binding; siRNA binding; RNA binding; enzyme binding; pre-mRNA binding; double-stranded RNA binding; identical protein binding; protein homodimerization activity; pre-miRNA binding; miRNA binding;
Cellular component	cytoplasm; cytosol; perinuclear region of cytoplasm; nucleus; nucleoplasm; nuclear body; RISC-loading complex; RISC complex;
Biological process	regulation of viral transcription; negative regulation of protein kinase activity; multicellular organism growth; positive regulation of translation; single fertilization; negative regulation of defense response to virus by host; spermatid development; positive regulation of viral genome replication; regulation of translation; production of miRNAs involved in gene silencing by miRNA; miRNA metabolic process; gene silencing; production of siRNA involved in RNA interference; pre-miRNA processing; regulation of production of miRNAs involved in gene silencing by miRNA; skeletal muscle tissue regeneration; positive regulation of muscle cell differentiation; neural precursor cell proliferation;
	Sources:Amigo / QuickGO
Orthologs
	6895
	21357
	ENSG00000139546
	ENSMUSG00000023051
	Q15633
	P97473
	NM_004178; NM_134323; NM_134324
	NM_001253795; NM_009319
	NP_004169; NP_599150; NP_599151
	NP_001240724; NP_033345
	Wikidata
View/Edit Human	View/Edit Mouse

RISC-loading complex subunit TARBP2 is a protein that in humans is encoded by the TARBP2 gene.