TAFA5

TAFA5
Identifiers
Aliases	TAFA5, QLLK5208, TAFA-5, UNQ5208, family with sequence similarity 19 (chemokine (C-C motif)-like), member A5, family with sequence similarity 19 member A5, C-C motif chemokine like, TAFA chemokine like family member 5, FAM19A5
External IDs	OMIM: 617499; MGI: 2146182; HomoloGene: 22888; GeneCards: TAFA5; OMA:TAFA5 - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	48,850,912 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	87,643,565 bp
RNA expression pattern
	Top expressed in
	cerebellar vermis; ; tibial nerve; ; Hypothalamus; ; Amygdala; ; hippocampus proper; ; entorhinal cortex; ; Brodmann area 9; ; postcentral gyrus; ; right frontal lobe; ; superior frontal gyrus;
	Top expressed in
	superior colliculus; ; central gray substance of midbrain; ; dorsal tegmental nucleus; ; lateral septal nucleus; ; nucleus of stria terminalis; ; anterior amygdaloid area; ; ventral tegmental area; ; inferior colliculi; ; dorsomedial hypothalamic nucleus; ; paraventricular nucleus of hypothalamus;
	More reference expression data
	n/a
Gene ontology
Molecular function	cytokine activity;
Cellular component	membrane; integral component of membrane; extracellular region; extracellular space;
Biological process	regulation of signaling receptor activity; signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	25817
	106014
	ENSG00000219438
	ENSMUSG00000054863
	Q7Z5A7
	Q91WE9
	NM_015381; NM_001082967
	NM_001252310; NM_134096
	NP_001076436; NP_056196
	NP_001239239; NP_598857
	Wikidata
View/Edit Human	View/Edit Mouse

Chemokine-like protein TAFA-5 is a protein that in humans is encoded by the TAFA5 gene.

This gene is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to CCL3, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to function as brain-specific chemokines or neurokines, that act as regulators of immune and nervous cells.