TAAR9

TAAR9
Identifiers
Aliases	TAAR9, TA3, TAR3, TAR9, TRAR3, trace amine associated receptor 9 (gene/pseudogene), trace amine associated receptor 9
External IDs	OMIM: 608282; MGI: 3527454; HomoloGene: 65286; GeneCards: TAAR9; OMA:TAAR9 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	132,539,336 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	23,985,432 bp
RNA expression pattern
	Top expressed in
	material anatomical entity;
	Top expressed in
	embryo; ; primary oocyte; ; secondary oocyte; ; zygote;
	More reference expression data
	n/a
Gene ontology
Molecular function	signal transducer activity; G protein-coupled receptor activity; trace-amine receptor activity;
Cellular component	plasma membrane; membrane; integral component of membrane;
Biological process	signal transduction; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	134860
	503558
	ENSG00000237110
	ENSMUSG00000037424
	Q96RI9
	Q5QD04
	NM_175057
	NM_001010831
	NP_778227
	NP_001010831
	Wikidata
View/Edit Human	View/Edit Mouse

Trace amine-associated receptor 9 is a protein that in humans is encoded by the TAAR9 gene.

TAAR9 is a member of a large family of rhodopsin G protein–coupled receptors (GPCRs, or GPRs). GPCRs contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.[supplied by OMIM] N-Methyl piperidine is a ligand of TAAR9 associated with aversive behavior in mice. N,N-dimethylcyclohexylamine is an additional binding agonist that also activaes TAAR7 variants.

TAAR9 gene deletion in rats leads to significantly decreased low-density lipoprotein cholesterol levels in the blood.