T7 DNA helicase

DNA primase/helicase
Crystal structure of T7 DNA helicase
Identifiers
OrganismEnterobacteria phage T7
Symbol4
UniProtP03692
Search for
StructuresSwiss-model
DomainsInterPro

T7 DNA helicase (gp4) is a hexameric motor protein encoded by T7 phages that uses energy from dTTP hydrolysis to process unidirectionally along single stranded DNA, separating (helicase) the two strands as it progresses. It is also a primase, making short stretches of RNA that initiates DNA synthesis. It forms a complex with T7 DNA polymerase. Its homologs are found in mitochondria (as Twinkle) and chloroplasts.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.