St. Mary's Anglo-Indian Higher Secondary School

St. Mary's Anglo-Indian Higher Secondary School is a Catholic higher secondary school for boys in Chennai, Tamil Nadu, India, operated by the Salesians of Don Bosco. It is located on Armenian Street, Broadway opposite the High Court and adjacent to St Mary's Co-Cathedral.

St. Mary's is one of the oldest schools in India, and one of the first five schools to be set up during the British period. It stands out today among the city schools for having often secured centum results in the Board Exams.