SYT7

SYT7
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2D8K
Identifiers
Aliases	SYT7, IPCA-7, IPCA7, PCANAP7, SYT-VII, SYTVII, synaptotagmin 7
External IDs	OMIM: 604146; MGI: 1859545; HomoloGene: 20889; GeneCards: SYT7; OMA:SYT7 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	61,581,148 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	10,430,544 bp
RNA expression pattern
	Top expressed in
	islet of Langerhans; ; right hemisphere of cerebellum; ; right frontal lobe; ; Brodmann area 9; ; prefrontal cortex; ; cerebellar vermis; ; cingulate gyrus; ; anterior cingulate cortex; ; right lobe of liver; ; pituitary gland;
	Top expressed in
	medial dorsal nucleus; ; medial geniculate nucleus; ; dentate gyrus; ; piriform cortex; ; substantia nigra; ; primary visual cortex; ; dentate gyrus of hippocampal formation granule cell; ; cerebellar cortex; ; cerebellar vermis; ; lobe of cerebellum;
	More reference expression data
	n/a
Gene ontology
Molecular function	calcium ion binding; metal ion binding; protein binding; SNARE binding; syntaxin binding; clathrin binding; phosphatidylinositol-4,5-bisphosphate binding; calcium-dependent phospholipid binding; calmodulin binding; phosphatidylserine binding;
Cellular component	integral component of membrane; membrane; synapse; synaptic vesicle membrane; cell junction; terminal bouton; dense core granule; extracellular exosome; cytoplasmic vesicle; transport vesicle membrane; cytosol; synaptic vesicle; presynaptic membrane; lysosome; peroxisome; peroxisomal membrane; phagocytic vesicle membrane; plasma membrane; lysosomal membrane; early phagosome; dendrite; soma; axon terminus; axon; neuron projection; exocytic vesicle; hippocampal mossy fiber to CA3 synapse; glutamatergic synapse; GABA-ergic synapse; integral component of presynaptic membrane;
Biological process	regulation of insulin secretion; positive regulation of calcium ion-dependent exocytosis; exocytosis; regulation of bone remodeling; plasma membrane repair; calcium-ion regulated exocytosis; regulation of calcium ion-dependent exocytosis; calcium ion-regulated exocytosis of neurotransmitter; regulation of glucagon secretion; phagosome-lysosome fusion; synaptic vesicle recycling; vesicle-mediated cholesterol transport; regulation of phagocytosis; vesicle fusion; calcium ion regulated lysosome exocytosis; phagocytosis; regulation of dopamine secretion; short-term synaptic potentiation; vesicle-mediated transport; cellular response to calcium ion; calcium-dependent activation of synaptic vesicle fusion; regulation of synaptic vesicle endocytosis;
	Sources:Amigo / QuickGO
Orthologs
	9066
	54525
	ENSG00000011347
	ENSMUSG00000024743
	O43581
	Q9R0N7
NM_001252065; NM_001300773; NM_004200; NM_001365809; NM_001370210;
	NM_001370211
	NM_018801; NM_173067; NM_173068; NM_001373944
NP_001238994; NP_001287702; NP_004191; NP_001352738; NP_001357139;
	NP_001357140
	NP_061271; NP_775090; NP_775091
	Wikidata
View/Edit Human	View/Edit Mouse

Synaptotagmin-7 is a protein that in humans is encoded by the SYT7 gene.