SUV39H2

SUV39H2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2R3A
Identifiers
Aliases	SUV39H2, KMT1B, suppressor of variegation 3-9 homolog 2, SUV39H2 histone lysine methyltransferase
External IDs	OMIM: 606503; MGI: 1890396; HomoloGene: 32548; GeneCards: SUV39H2; OMA:SUV39H2 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	14,904,315 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	3,476,068 bp
RNA expression pattern
	Top expressed in
	sperm; ; secondary oocyte; ; left testis; ; right testis; ; ventricular zone; ; ganglionic eminence; ; gonad; ; testicle; ; stromal cell of endometrium; ; islet of Langerhans;
	Top expressed in
	tail of embryo; ; secondary oocyte; ; genital tubercle; ; zygote; ; spermatid; ; primary oocyte; ; ventricular zone; ; epiblast; ; primitive streak; ; embryo;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	methyltransferase activity; transferase activity; histone methyltransferase activity (H3-K9 specific); transcription cis-regulatory region binding; metal ion binding; protein binding; histone-lysine N-methyltransferase activity; zinc ion binding; S-adenosyl-L-methionine binding;
Cellular component	chromosome; nucleoplasm; chromatin; chromosome, centromeric region; nucleus;
Biological process	chromatin remodeling; cell differentiation; regulation of transcription, DNA-templated; rhythmic process; histone H3-K9 dimethylation; negative regulation of circadian rhythm; negative regulation of transcription by RNA polymerase II; transcription, DNA-templated; histone H3-K9 trimethylation; methylation; histone lysine methylation; cell cycle; negative regulation of transcription, DNA-templated; cellular response to hypoxia; chromatin organization;
	Sources:Amigo / QuickGO
Orthologs
	79723
	64707
	ENSG00000152455
	ENSMUSG00000026646
	Q9H5I1
	Q9EQQ0
	NM_001193424; NM_001193425; NM_001193426; NM_001193427; NM_024670
	NM_022724
	NP_001180353; NP_001180354; NP_001180355; NP_001180356; NP_078946
	NP_073561
	Wikidata
View/Edit Human	View/Edit Mouse

Histone-lysine N-methyltransferase SUV39H2 is an enzyme that in humans is encoded by the SUV39H2 gene.