STH (gene)

STH
Identifiers
Aliases	STH, MAPTIT, saitohin
External IDs	OMIM: 607067; HomoloGene: 88448; GeneCards: STH; OMA:STH - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	45,999,694 bp
RNA expression pattern
	Top expressed in
	testicle; ; corpus callosum; ; cerebellar hemisphere; ; right hemisphere of cerebellum; ; skeletal muscle tissue; ; gastrocnemius muscle; ; caudate nucleus; ; right frontal lobe; ; Hypothalamus; ; hippocampus proper;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding;
Cellular component	nucleus; cytoplasm; perinuclear region of cytoplasm;
Biological process	positive regulation of mRNA splicing, via spliceosome;
	Sources:Amigo / QuickGO
Orthologs
	246744
	n/a
	ENSG00000256762; ENSG00000281139
	n/a
	Q8IWL8
	n/a
	NM_001007532
	n/a
	NP_001007533
	n/a
	Wikidata
View/Edit Human

Saitohin is a protein that in humans is encoded by the STH gene. This intronless gene encodes for 128 amino acids in an open reading frame. It is located in the human tau gene, in the intron between exons 9 and 10. Also, a single polymorphism of a nucleotide is seen through a change of glutamine residue 7(Q7R) to arginine. It is found to be susceptible to multiple degenerative diseases, however, the exact function of the gene is still unknown.