ST14

ST14
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1EAW, 1EAX, 2GV6, 2GV7, 3BN9, 3NCL, 3P8F, 3P8G, 3SO3, 4IS5, 4ISL, 4ISN, 4ISO, 4JYT, 4JZ1, 4JZI, 4O97, 4O9V, 4R0I
Identifiers
Aliases	ST14, ARCI11, HAI, MT-SP1, MTSP1, PRSS14, SNC19, TADG15, TMPRSS14, suppression of tumorigenicity 14, ST14 transmembrane serine protease matriptase, CAP3
External IDs	OMIM: 606797; MGI: 1338881; HomoloGene: 7906; GeneCards: ST14; OMA:ST14 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	130,210,362 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	31,043,149 bp
RNA expression pattern
	Top expressed in
	mucosa of transverse colon; ; nasal epithelium; ; duodenum; ; mucosa of ileum; ; mucosa of pharynx; ; jejunal mucosa; ; olfactory zone of nasal mucosa; ; rectum; ; gingival epithelium; ; mucosa of sigmoid colon;
	Top expressed in
	hair follicle; ; intestinal villus; ; crypt of lieberkuhn of small intestine; ; gastric mucosa; ; mucous cell of stomach; ; large intestine; ; colon; ; epithelium of stomach; ; lip; ; Eustachian tube;
	More reference expression data
	n/a
Gene ontology
Molecular function	peptidase activity; serine-type peptidase activity; hydrolase activity; endopeptidase activity; serine-type endopeptidase activity;
Cellular component	integral component of membrane; extracellular region; plasma membrane; basolateral plasma membrane; integral component of plasma membrane; extrinsic component of plasma membrane; membrane; extracellular space;
Biological process	neural tube closure; epithelial cell morphogenesis involved in placental branching; proteolysis; keratinocyte differentiation; cornification;
	Sources:Amigo / QuickGO
Orthologs
	6768
	19143
	ENSG00000149418
	ENSMUSG00000031995
	Q9Y5Y6
	P56677
	NM_021978
	NM_011176
	NP_068813
	NP_035306
	Wikidata
View/Edit Human	View/Edit Mouse

Suppressor of tumorigenicity 14 protein, also known as matriptase, is a protein that in humans is encoded by the ST14 gene. ST14 orthologs have been identified in most mammals for which complete genome data are available.