SNX21

SNX21
Identifiers
Aliases	SNX21, C20orf161, PP3993, SNX-L, dJ337O18.4, sorting nexin family member 21, SNXL
External IDs	MGI: 1917729; HomoloGene: 43132; GeneCards: SNX21; OMA:SNX21 - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	45,843,276 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	164,635,736 bp
RNA expression pattern
	Top expressed in
	skin of leg; ; right ovary; ; left ovary; ; skin of abdomen; ; right coronary artery; ; endothelial cell; ; right adrenal cortex; ; gastric mucosa; ; left adrenal cortex; ; left uterine tube;
	Top expressed in
	muscle of thigh; ; Rostral migratory stream; ; lip; ; lumbar spinal ganglion; ; superior frontal gyrus; ; primary visual cortex; ; facial motor nucleus; ; right kidney; ; cerebellar cortex; ; neural layer of retina;
	More reference expression data
	n/a
Gene ontology
Molecular function	lipid binding; phosphatidylinositol binding; phosphatidylinositol-4,5-bisphosphate binding; phosphatidylinositol-3-phosphate binding;
Cellular component	membrane; cytoplasmic vesicle; cytoplasmic vesicle membrane; endosome; early endosome membrane;
Biological process	protein transport;
	Sources:Amigo / QuickGO
Orthologs
	90203
	101113
	ENSG00000124104
	ENSMUSG00000050373
	Q969T3
	Q3UR97
	NM_001042632; NM_001042633; NM_033421; NM_152897
	NM_133924; NM_001399716
	NP_001036097; NP_001036098; NP_219489; NP_690857
	NP_598685; NP_001386645
	Wikidata
View/Edit Human	View/Edit Mouse

Sorting nexin-21 is a protein that in humans is encoded by the SNX21 gene.

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members. The specific function of this protein has not been determined. Multiple transcript variants encoding distinct isoforms have been identified for this gene.