SLIT3

SLIT3
Identifiers
Aliases	SLIT3, MEGF5, SLIL2, SLIT1, Slit-3, slit2, slit guidance ligand 3
External IDs	OMIM: 603745; MGI: 1315202; HomoloGene: 2303; GeneCards: SLIT3; OMA:SLIT3 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	169,301,139 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	35,599,334 bp
RNA expression pattern
	Top expressed in
	right coronary artery; ; popliteal artery; ; tibial arteries; ; saphenous vein; ; gallbladder; ; cardiac muscle tissue of right atrium; ; vena cava; ; subcutaneous adipose tissue; ; left coronary artery; ; right auricle of heart;
	Top expressed in
	umbilical cord; ; gastrula; ; genital tubercle; ; paramesonephric duct; ; ascending aorta; ; tail of embryo; ; lip; ; superior cervical ganglion; ; skin of external ear; ; cardiac muscle tissue of atrium;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	Roundabout binding; calcium ion binding; heparin binding;
Cellular component	extracellular region; mitochondrion; extracellular space;
Biological process	negative regulation of chemokine-mediated signaling pathway; chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration; cell differentiation; negative chemotaxis; Roundabout signaling pathway; negative regulation of gene expression; nervous system development; multicellular organism development; cellular response to hormone stimulus; negative regulation of cell growth; response to cortisol; apoptotic process involved in luteolysis; animal organ morphogenesis; axon extension involved in axon guidance; negative regulation of cell population proliferation; axon guidance; aortic valve morphogenesis; atrioventricular valve morphogenesis; ventricular septum morphogenesis;
	Sources:Amigo / QuickGO
Orthologs
	6586
	20564
	ENSG00000184347
	ENSMUSG00000056427
	O75094
	Q9WVB4
	NM_003062; NM_001271946
	NM_011412
	NP_001258875; NP_003053
	NP_035542
	Wikidata
View/Edit Human	View/Edit Mouse

Slit homolog 3 protein is a protein that in humans is encoded by the SLIT3 gene.