UDP-galactose translocator

SLC35A2
Identifiers
Aliases	SLC35A2, CDG2M, CDGX, UDP-Gal-Tr, UGALT, UGAT, UGT, UGT1, UGT2, UGTL, solute carrier family 35 member A2
External IDs	OMIM: 314375; MGI: 1345297; HomoloGene: 136614; GeneCards: SLC35A2; OMA:SLC35A2 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	48,911,958 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	7,760,731 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; bronchial epithelial cell; ; palpebral conjunctiva; ; stromal cell of endometrium; ; mucosa of transverse colon; ; olfactory zone of nasal mucosa; ; mucosa of sigmoid colon; ; rectum; ; epithelium of nasopharynx; ; right uterine tube;
	Top expressed in
	left colon; ; Paneth cell; ; cumulus cell; ; ascending aorta; ; aortic valve; ; crypt of lieberkuhn of small intestine; ; motor neuron; ; lobe of prostate; ; seminal vesicula; ; lacrimal gland;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; UDP-galactose transmembrane transporter activity; pyrimidine nucleotide-sugar transmembrane transporter activity;
Cellular component	integral component of membrane; Golgi membrane; Golgi apparatus; endoplasmic reticulum; nucleus; membrane; integral component of Golgi membrane;
Biological process	galactose metabolic process; carbohydrate transport; UDP-galactose transmembrane transport; pyrimidine nucleotide-sugar transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	7355
	22232
	ENSG00000102100
	ENSMUSG00000031156
	P78381
	Q9R0M8
NM_005660; NM_001032289; NM_001042498; NM_001282647; NM_001282648;
	NM_001282649; NM_001282650; NM_001282651
	NM_001083937; NM_078484
NP_001027460; NP_001035963; NP_001269576; NP_001269577; NP_001269578;
	NP_001269579; NP_001269580; NP_005651
	NP_001077406; NP_511039
	Wikidata
View/Edit Human	View/Edit Mouse

UDP-galactose translocator is a protein that in humans is encoded by the SLC35A2 gene.

Somatic loss-of-function variants in the SLC35A2 gene were originally associated with focal epilepsy with radiographically nonlesional epilepsy. Later it was discovered that individuals with somatic variants in SLC35A2 have a mild malformation of cortical development with oligodendroglial hyperplasia in epilepsy (MOGHE), which is a subtype of frontal lobe epilepsy.