SIK1

SIK1
Identifiers
Aliases	SIK1, MSK, SIK, SNF1LK, EIEE30, salt inducible kinase 1, SIK-1, SIK1B, DEE30
External IDs	OMIM: 605705; MGI: 104754; HomoloGene: 136094; GeneCards: SIK1; OMA:SIK1 - orthologs
Gene location (Human)
Chr.	Chromosome 21 (human)
End	43,427,131 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	32,074,778 bp
RNA expression pattern
	Top expressed in
	gastric mucosa; ; skin of abdomen; ; skin of leg; ; gallbladder; ; bone marrow cells; ; left ovary; ; left uterine tube; ; vagina; ; right ovary; ; upper lobe of left lung;
	Top expressed in
	granulocyte; ; decidua; ; yolk sac; ; lip; ; muscle of thigh; ; genital tubercle; ; proximal tubule; ; tail of embryo; ; esophagus; ; endocardial cushion;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	transferase activity; nucleotide binding; protein kinase activity; cAMP response element binding protein binding; 14-3-3 protein binding; metal ion binding; kinase activity; protein serine/threonine kinase activity; protein binding; ATP binding; protein kinase binding; magnesium ion binding;
Cellular component	cytoplasm; nucleus; nucleotide-activated protein kinase complex;
Biological process	regulation of myotube differentiation; cell differentiation; intracellular signal transduction; phosphorylation; regulation of sodium ion transport; rhythmic process; cardiac muscle cell differentiation; negative regulation of triglyceride biosynthetic process; negative regulation of CREB transcription factor activity; multicellular organism development; protein phosphorylation; negative regulation of gluconeogenesis; regulation of mitotic cell cycle; regulation of cell differentiation; protein autophosphorylation; cell cycle; positive regulation of anoikis; entrainment of circadian clock by photoperiod; cellular response to hormone stimulus; negative regulation of TOR signaling; cellular response to glucose starvation;
	Sources:Amigo / QuickGO
Orthologs
	150094
	17691
	ENSG00000142178
	ENSMUSG00000024042
	P57059
	Q60670
	NM_173354
	NM_010831
	NP_001307572
	NP_034961
	Wikidata
View/Edit Human	View/Edit Mouse

Serine/threonine-protein kinase SIK1 is an enzyme that in humans is encoded by the SIK1 gene.