SH3KBP1

SH3KBP1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2BZ8, 2K6D, 2K9G, 2O2O, 2YDL, 5ABS, 2N64
Identifiers
Aliases	SH3KBP1, CD2BP3, CIN85, GIG10, HSB-1, HSB1, MIG18, SH3 domain containing kinase binding protein 1, IMD61, AGMX2
External IDs	OMIM: 300374; MGI: 1889583; HomoloGene: 10971; GeneCards: SH3KBP1; OMA:SH3KBP1 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	19,887,600 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	158,761,065 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; myocardium of left ventricle; ; mucosa of ileum; ; lateral nuclear group of thalamus; ; skin of arm; ; cardiac muscle tissue of right atrium; ; inferior ganglion of vagus nerve; ; subthalamic nucleus; ; blood; ; white blood cell;
	Top expressed in
	thymus; ; zygote; ; myocardium of ventricle; ; right ventricle; ; granulocyte; ; cardiac muscles; ; atrioventricular valve; ; secondary oocyte; ; stroma of bone marrow; ; extraocular muscle;
	More reference expression data
	n/a
Gene ontology
Molecular function	SH3 domain binding; protein binding;
Cellular component	cytosol; membrane; cell-cell junction; focal adhesion; plasma membrane; endocytic vesicle; synapse; cell junction; neuron projection; cytoskeleton; cytoplasmic vesicle membrane; cytoplasmic vesicle; cytoplasm;
Biological process	negative regulation of epidermal growth factor receptor signaling pathway; endocytosis; cell-cell signaling; cytoskeleton organization; regulation of cell shape; cell migration; apoptotic process; membrane organization; axon guidance; actin filament organization;
	Sources:Amigo / QuickGO
Orthologs
	30011
	58194
	ENSG00000147010
	ENSMUSG00000040990
	Q96B97; Q5JPT2
	Q8R550
NM_001024666; NM_001184960; NM_031892; NM_001353890; NM_001353891;
	NM_001353892; NM_001353893; NM_001353894; NM_001353895; NM_001353897
NM_001135727; NM_001135728; NM_001290661; NM_001290664; NM_021389;
	NM_001374701
NP_001019837; NP_001171889; NP_114098; NP_001340819; NP_001340820;
	NP_001340821; NP_001340822; NP_001340823; NP_001340824; NP_001340826
NP_001129199; NP_001129200; NP_001277590; NP_001277593; NP_067364;
	NP_001361630
	Wikidata
View/Edit Human	View/Edit Mouse

SH3 domain-containing kinase-binding protein 1 (synonyms - CIN85, in rodents - Ruk) is an adaptor protein that in humans is encoded by the SH3KBP1 gene.