SGTA

SGTA
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2VYI, 4CPG, 4GOD, 4GOE, 4GOF
Identifiers
Aliases	SGTA, SGT, alphaSGT, hSGT, small glutamine rich tetratricopeptide repeat containing alpha, small glutamine rich tetratricopeptide repeat co-chaperone alpha, SGT1, Vpu
External IDs	OMIM: 603419; MGI: 1098703; HomoloGene: 31122; GeneCards: SGTA; OMA:SGTA - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	2,783,362 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	80,896,015 bp
RNA expression pattern
	Top expressed in
	apex of heart; ; C1 segment; ; muscle of thigh; ; gastrocnemius muscle; ; right frontal lobe; ; middle frontal gyrus; ; right auricle of heart; ; paraflocculus of cerebellum; ; cingulate gyrus; ; anterior pituitary;
	Top expressed in
	perirhinal cortex; ; entorhinal cortex; ; ventricular zone; ; primary visual cortex; ; yolk sac; ; muscle of thigh; ; lip; ; superior frontal gyrus; ; lactiferous gland; ; neural tube;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; BAT3 complex binding; protein self-association; identical protein binding; molecular adaptor activity;
Cellular component	cytosol; membrane; nucleus; cytoplasm; presynapse; extrinsic component of synaptic vesicle membrane; TRC complex;
Biological process	positive regulation of ER-associated ubiquitin-dependent protein catabolic process; viral process; ubiquitin-dependent ERAD pathway; negative regulation of ER-associated ubiquitin-dependent protein catabolic process; negative regulation of ubiquitin-dependent protein catabolic process; tail-anchored membrane protein insertion into ER membrane; chaperone-mediated protein folding; posttranslational protein targeting to endoplasmic reticulum membrane; positive regulation of chaperone-mediated protein folding;
	Sources:Amigo / QuickGO
Orthologs
	6449
	52551
	ENSG00000104969
	ENSMUSG00000004937
	O43765
	Q8BJU0
	NM_003021
	NM_024499; NM_001358549; NM_001358550
	NP_003012
	NP_078775; NP_001345478; NP_001345479
	Wikidata
View/Edit Human	View/Edit Mouse

Small glutamine-rich tetratricopeptide repeat-containing protein alpha is a protein that in humans is encoded by the SGTA gene. SGTA orthologs have also been identified in several mammals for which complete genome data are available. STGA belongs to a family of co-chaperone proteins that obtain a TPR motif. STGA was discovered just 15 years ago.