SGMS1

SGMS1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2D8C
Identifiers
Aliases	SGMS1, MOB, MOB1, SMS1, TMEM23, hmob33, sphingomyelin synthase 1
External IDs	OMIM: 611573; MGI: 2444110; HomoloGene: 27040; GeneCards: SGMS1; OMA:SGMS1 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	50,625,163 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	32,389,714 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; palpebral conjunctiva; ; retinal pigment epithelium; ; Epithelium of choroid plexus; ; germinal epithelium; ; corpus callosum; ; hair follicle; ; skin of thigh; ; C1 segment; ; skin of hip;
	Top expressed in
	spermatid; ; seminiferous tubule; ; retinal pigment epithelium; ; Epithelium of choroid plexus; ; sciatic nerve; ; left lung lobe; ; interventricular septum; ; vestibular membrane of cochlear duct; ; right lung lobe; ; spermatocyte;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	kinase activity; transferase activity; ceramide cholinephosphotransferase activity; sphingomyelin synthase activity; ceramide phosphoethanolamine synthase activity;
Cellular component	integral component of membrane; integral component of Golgi membrane; Golgi trans cisterna; Golgi membrane; plasma membrane; Golgi apparatus; endoplasmic reticulum; nucleus; membrane; integral component of plasma membrane; integral component of endoplasmic reticulum membrane;
Biological process	lipid metabolism; sphingomyelin biosynthetic process; sphingolipid biosynthetic process; phosphorylation; apoptotic process; sphingolipid metabolic process; ceramide biosynthetic process; regulation of intrinsic apoptotic signaling pathway; inflammatory response; positive regulation of gene expression; cellular response to lipopolysaccharide; cellular response to tumor necrosis factor;
	Sources:Amigo / QuickGO
Orthologs
	259230
	208449
	ENSG00000198964
	ENSMUSG00000040451
	Q86VZ5
	Q8VCQ6
	NM_147156
	NM_001168525; NM_001168526; NM_144792; NM_001362423
	NP_671512
	NP_001161997; NP_001161998; NP_659041; NP_001349352
	Wikidata
View/Edit Human	View/Edit Mouse

Phosphatidylcholine:ceramide cholinephosphotransferase 1 is an enzyme that in humans is encoded by the SGMS1 gene.