Restless legs syndrome

Restless legs syndrome
Other namesWillis–Ekbom disease (WED), Wittmaack–Ekbom syndrome
Sleep pattern of a person with restless legs syndrome (red) compared to a healthy sleep pattern (blue)
SpecialtySleep medicine
SymptomsUnpleasant feeling in the legs that briefly improves with moving them
ComplicationsDaytime sleepiness, low energy, irritability, sadness
Usual onsetMore common with older age
Risk factorsLow iron levels, kidney failure, Parkinson's disease, diabetes mellitus, rheumatoid arthritis, pregnancy, certain medications
Diagnostic methodBased on symptoms after ruling out other possible causes
TreatmentLifestyle changes, medication
MedicationDopamine agonists, levodopa, gabapentinoids, opioids
Frequency2.5–15% (US)

Restless legs syndrome (RLS), also known as Willis–Ekbom disease (WED), is a neurological disorder, usually chronic, that causes an overwhelming urge to move one's legs. There is often an unpleasant feeling in the legs that improves temporarily by moving them. This feeling is often described as aching, tingling, or crawling in nature. Occasionally, arms may also be affected. The feelings generally happen when at rest and therefore can make it hard to sleep. Sleep disruption may leave people with RLS sleepy during the day, with low energy, and irritable or depressed. Additionally, many have limb twitching during sleep, a condition known as periodic limb movement disorder. RLS is not the same as habitual foot-tapping or leg-rocking.