Ramucirumab

Ramucirumab
Monoclonal antibody
TypeWhole antibody
SourceHuman
TargetVEGFR2 (KDR)
Clinical data
Trade namesCyramza
Other namesLY3009806, IMC-1121B
AHFS/Drugs.comMonograph
MedlinePlusa614026
License data
Routes of
administration
Intravenous infusion
Drug classAntineoplastic agents
ATC code
Legal status
Legal status
Identifiers
CAS Number
DrugBank
ChemSpider
  • none
UNII
Chemical and physical data
FormulaC6374H9864N1692O1996S46
Molar mass143609.63 g·mol−1
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Ramucirumab(), sold under the brand name Cyramza, is a fully human monoclonal antibody (IgG1) used for the treatment of cancer. Ramucirumab is a human vascular endothelial growth factor receptor 2 (VEGFR2) antagonist. Ramucirumab was developed by ImClone Systems.