RBP3

RBP3
Identifiers
Aliases	RBP3, D10S64, D10S65, D10S66, IRBP, RBPI, RP66, retinol binding protein 3
External IDs	OMIM: 180290; MGI: 97878; HomoloGene: 9261; GeneCards: RBP3; OMA:RBP3 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	47,357,881 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	33,686,173 bp
RNA expression pattern
	Top expressed in
	testicle; ; retinal pigment epithelium; ; Epithelium of choroid plexus; ; hippocampal formation; ; hippocampus proper; ; Mesencephalon; ; frontal lobe; ; Cortex of frontal lobe; ; prefrontal cortex; ; substantia nigra;
	Top expressed in
	neural layer of retina; ; epithelium of lens; ; retinal pigment epithelium; ; pineal gland; ; outer nuclear layer; ; right ventricle; ; embryo; ; lumbar subsegment of spinal cord; ; iris; ; embryo;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	serine-type peptidase activity; retinoid binding; retinal binding; retinol binding;
Cellular component	extracellular vesicle; extracellular region; interphotoreceptor matrix; extracellular space; cone matrix sheath;
Biological process	proteolysis; retinoid metabolic process; lipid metabolism; visual perception; transport;
	Sources:Amigo / QuickGO
Orthologs
	5949
	19661
	ENSG00000265203
	ENSMUSG00000041534
	P10745
	P49194
	NM_002900
	NM_015745
	NP_002891
	NP_056560
	Wikidata
View/Edit Human	View/Edit Mouse

Retinol-binding protein 3, interstitial (RBP3), also known as interphotoreceptor retinoid-binding protein (IRBP), is a protein that in humans is encoded by the RBP3 gene. RBP3 orthologs have been identified in most eutherians except tenrecs and armadillos. A horizontal gene transfer from bacteria has been proposed to explain the evolution of the eye in chordates.