RACGAP1

RACGAP1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2OVJ, 3W6R, 3WPQ, 3WPS, 4B6D, 5C2J, 5C2K
Identifiers
Aliases	RACGAP1, CYK4, HsCYK-4, ID-GAP, MgcRacGAP, Rac GTPase activating protein 1, CDAN3B
External IDs	OMIM: 604980; MGI: 1349423; HomoloGene: 8077; GeneCards: RACGAP1; OMA:RACGAP1 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	50,033,136 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	99,549,537 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; ganglionic eminence; ; trabecular bone; ; sperm; ; secondary oocyte; ; oral cavity; ; bone marrow; ; amniotic fluid; ; gonad; ; right testis;
	Top expressed in
	ventricular zone; ; spermatocyte; ; spermatid; ; endocardial cushion; ; yolk sac; ; dermis; ; atrioventricular valve; ; atrium; ; thymus; ; ganglionic eminence;
	More reference expression data
	n/a
Gene ontology
Molecular function	microtubule binding; alpha-tubulin binding; metal ion binding; protein binding; beta-tubulin binding; gamma-tubulin binding; protein kinase binding; phosphatidylinositol-3,4,5-trisphosphate binding; lipid binding; GTPase activator activity;
Cellular component	cytoplasm; cytosol; centralspindlin complex; membrane; extrinsic component of cytoplasmic side of plasma membrane; plasma membrane; spindle; nucleoplasm; acrosomal vesicle; spindle midzone; cleavage furrow; mitotic spindle; microtubule; extracellular exosome; cytoskeleton; nucleus; cytoplasmic vesicle; midbody; Flemming body;
Biological process	cell differentiation; intracellular signal transduction; antigen processing and presentation of exogenous peptide antigen via MHC class II; mitotic spindle midzone assembly; sulfate transport; mitotic cytokinesis; ion transport; cell division; positive regulation of cytokinesis; multicellular organism development; microtubule-based movement; actomyosin contractile ring assembly; spermatogenesis; neuroblast proliferation; cell cycle; regulation of attachment of spindle microtubules to kinetochore; regulation of small GTPase mediated signal transduction; signal transduction; positive regulation of GTPase activity; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; regulation of embryonic development; transport;
	Sources:Amigo / QuickGO
Orthologs
	29127
	26934
	ENSG00000161800
	ENSMUSG00000023015
	Q9H0H5
	Q9WVM1
NM_001126103; NM_001126104; NM_013277; NM_001319999; NM_001320000;
	NM_001320001; NM_001320002; NM_001320003; NM_001320004; NM_001320005; NM_001320006; NM_001320007
	NM_001253808; NM_001253809; NM_012025
NP_001119575; NP_001119576; NP_001306928; NP_001306929; NP_001306930;
	NP_001306931; NP_001306932; NP_001306933; NP_001306934; NP_001306935; NP_001306936; NP_037409
	NP_001240737; NP_001240738; NP_036155
	Wikidata
View/Edit Human	View/Edit Mouse

Rac GTPase-activating protein 1 is an enzyme that in humans is encoded by the RACGAP1 gene.