RAB5A

RAB5A
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1N6H, 1N6I, 1N6K, 1N6L, 1N6N, 1N6O, 1N6P, 1N6R, 1R2Q, 1TU3, 1TU4, 3MJH, 4Q9U
Identifiers
Aliases	RAB5A, RAB5, member RAS oncogene family
External IDs	OMIM: 179512; MGI: 105926; HomoloGene: 68142; GeneCards: RAB5A; OMA:RAB5A - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	19,985,175 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	53,814,708 bp
RNA expression pattern
	Top expressed in
	gingival epithelium; ; endothelial cell; ; lower lobe of lung; ; skin of thigh; ; corpus epididymis; ; Pons; ; pars compacta; ; human penis; ; pars reticulata; ; Medulla Oblongata;
	Top expressed in
	esophagus; ; ganglionic eminence; ; hippocampus proper; ; lens; ; primary visual cortex; ; cerebellar cortex; ; right kidney; ; zone of skin; ; superior frontal gyrus; ; neural tube;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; GDP binding; GTP binding; protein binding; GTPase activity; guanyl nucleotide binding;
Cellular component	cytoplasm; axon terminus; endosome; cell projection; membrane; synaptic vesicle; melanosome; ruffle; plasma membrane; endocytic vesicle; axon; soma; terminal bouton; dendrite; somatodendritic compartment; early endosome; phagocytic vesicle; actin cytoskeleton; membrane raft; cytoplasmic side of early endosome membrane; extracellular exosome; cytoplasmic vesicle; phagocytic vesicle membrane; cytosol; endosome membrane; clathrin-coated vesicle membrane; early endosome membrane; early phagosome; postsynaptic early endosome; anchored component of synaptic vesicle membrane;
Biological process	regulation of endocytosis; regulation of filopodium assembly; endocytosis; blood coagulation; receptor internalization involved in canonical Wnt signaling pathway; regulation of autophagosome assembly; synaptic vesicle recycling; early endosome to late endosome transport; transport; protein transport; positive regulation of exocytosis; regulation of synaptic vesicle exocytosis; regulation of endosome size; viral RNA genome replication; phagocytosis; phosphatidylinositol biosynthetic process; membrane organization; post-translational protein modification; intracellular protein transport; Rab protein signal transduction; regulation of long-term neuronal synaptic plasticity; amyloid-beta clearance by transcytosis;
	Sources:Amigo / QuickGO
Orthologs
	5868
	271457
	ENSG00000144566
	ENSMUSG00000017831
	P20339
	Q9CQD1
	NM_004162; NM_001292048
	NM_025887
	NP_001278977; NP_004153
	NP_080163
	Wikidata
View/Edit Human	View/Edit Mouse

Ras-related protein Rab-5A is a protein that in humans is encoded by the RAB5A gene.