Protein C deficiency

Protein C deficiency
Other namesTHPH3
This condition is inherited in an autosomal dominant manner.
SpecialtyHematology 

Protein C deficiency is a rare genetic trait that predisposes to thrombotic disease. It was first described in 1981. The disease belongs to a group of genetic disorders known as thrombophilias. Protein C deficiency is associated with an increased incidence of venous thromboembolism (relative risk 8–10), whereas no association with arterial thrombotic disease has been found.

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