Propantheline bromide

Propantheline bromide
Clinical data
Trade namesPro-Banthine, others
AHFS/Drugs.comMonograph
MedlinePlusa684020
Routes of
administration
By mouth
Drug classAntimuscarinic
ATC code
Identifiers
  • N-isopropyl-N-methyl-N-{2-[(9H-xanthen-9-ylcarbonyl)oxy]ethyl}propan-2-aminium bromide
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.000.028
Chemical and physical data
FormulaC23H30NO3
Molar mass368.497 g·mol−1
3D model (JSmol)
  • [Br-].O=C(OCC[N+](C(C)C)(C(C)C)C)C2c3c(Oc1c2cccc1)cccc3
  • InChI=1S/C23H30NO3.BrH/c1-16(2)24(5,17(3)4)14-15-26-23(25)22-18-10-6-8-12-20(18)27-21-13-9-7-11-19(21)22;/h6-13,16-17,22H,14-15H2,1-5H3;1H/q+1;/p-1 Y
  • Key:XLBIBBZXLMYSFF-UHFFFAOYSA-M Y
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Propantheline bromide (INN) is an antimuscarinic medication used for the treatment of excessive sweating (hyperhidrosis), cramps or spasms of the stomach, intestines (gut), or bladder, and involuntary urination (enuresis). It can also be used to control the symptoms of irritable bowel syndrome (IBS) and similar conditions. This medication can also be used for patients who experience intense gastrointestinal symptoms while tapering off tricyclic antidepressants.