Powerful Stuff is a 1989 studio album by Texas based blues rock band The Fabulous Thunderbirds. It was recorded in Memphis and produced by Terry Manning.
It was the last studio album to feature Jimmie Vaughan before leaving for a solo career. The track "Powerful Stuff" achieved mainstream success and was featured in Touchstone Pictures' 1988 hit film Cocktail. It was the first single released from the Cocktail soundtrack album, which reached number one on the Billboard Charts and sold over 19 million copies worldwide.