Orthostatic albuminuria

Orthostatic albuminuria
Other namesOrthostatic proteinuria, Postural proteinuria, Postural albuminuria.
The structure of Human serum albumin (HSA) complexed with 6 palmitic acid molecules
Pronunciation
  • ȯr-thə-ˈsta-tik /ælˌbjuməˈn(j)ʊriə/
SpecialtyUrology 
Usual onsetUnder 30 years old
Diagnostic methodUrine test strip, Urine protein/creatinine ratio, 24 hour urine collection, renal function tests, and urine microscopy.
Differential diagnosisTransient proteinuria
PrognosisBenign.
Frequency3 to 5% of adults and teenagers

Orthostatic albuminuria, also known as orthostatic proteinuria is defined by raised levels of urine protein excretion while in an upright position. In orthostatic albuminuria urine protein excretion returns to normal while in a supine position, such as laying down. Orthostatic albuminuria is the most common cause of isolated proteinuria in those under 20. The prevalence of orthostatic albuminuria is suspected to be between 2 and 5%, however some studies suggest that it is more common. Orthostatic albuminuria is diagnosed if urine protein levels are normal in a morning urine sample and there are no other obvious causes of albuminuria. Patients with orthostatic albuminuria are often asymptomatic and there is no indication for any type of treatment or interventions.