Porcine circovirus

Porcine circovirus
Scientific classification
(unranked): Virus
Realm: Monodnaviria
Kingdom: Shotokuvirae
Phylum: Cressdnaviricota
Class: Arfiviricetes
Order: Cirlivirales
Family: Circoviridae
Genus: Circovirus
Groups included
  • Circovirus porcine1 (Porcine circovirus 1)
  • Circovirus porcine2 (Porcine circovirus 2)
  • Circovirus porcine3 (Porcine circovirus 3)
  • Circovirus porcine4 (Porcine circovirus 4)
Cladistically included but traditionally excluded taxa
  • All other circoviruses

Porcine circovirus (PCV) is a group of four single-stranded DNA viruses that are non-enveloped with an unsegmented circular genome. They are members of the genus Circovirus that can infect pigs. The viral capsid is icosahedral and approximately 17 nm in diameter.

PCVs are the smallest viruses replicating autonomously in eukaryotic cells. They replicate in the nucleus of infected cells, using the host polymerase for genome amplification.

PCV-2 causes Porcine circovirus associated disease or postweaning multisystemic wasting syndrome (PMWS). An effective vaccination is now available. Fort Dodge Animal Health (Wyeth) launched the first USDA approved vaccine in 2006, containing an inactivated virus (ATCvet code: QI09AA07 (WHO)).

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