Pilocytic astrocytoma

Pilocytic astrocytoma
Other namesJuvenile pilocytic astrocytoma or Cystic cerebellar astrocytoma
Micrograph of a pilocytic astrocytoma, showing characteristic bipolar cells with long pilocytic (hair-like) processes. Smear preparation. H&E stain.
SpecialtyNeuro-oncology, neurosurgery
Symptomslack of appropriate weight gain/ weight loss
headaches
nausea
vomiting
irritability
torticollis
difficulty to coordinate movements
Usual onsetFirst 20 years of life
Diagnostic methodMRI, CT scan

Pilocytic astrocytoma (and its variant pilomyxoid astrocytoma) is a brain tumor that occurs most commonly in children and young adults (in the first 20 years of life). They usually arise in the cerebellum, near the brainstem, in the hypothalamic region, or the optic chiasm, but they may occur in any area where astrocytes are present, including the cerebral hemispheres and the spinal cord. These tumors are usually slow growing and benign, corresponding to WHO malignancy grade 1.