PTPRM

PTPRM
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1RPM, 2C9A, 2V5Y
Identifiers
Aliases	PTPRM, PTPRL1, R-PTP-MU, RPTPM, RPTPU, hR-PTPu, protein tyrosine phosphatase, receptor type M, protein tyrosine phosphatase receptor type M
External IDs	OMIM: 176888; MGI: 102694; HomoloGene: 37694; GeneCards: PTPRM; OMA:PTPRM - orthologs
Gene location (Human)
Chr.	Chromosome 18 (human)
End	8,406,861 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	67,661,452 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; visceral pleura; ; right lung; ; Achilles tendon; ; lateral nuclear group of thalamus; ; tibia; ; left lobe of thyroid gland; ; right lobe of thyroid gland; ; subcutaneous adipose tissue; ; ventricle of the heart;
	Top expressed in
	left lung lobe; ; right ventricle; ; right lung; ; cardiac muscle tissue of left ventricle; ; right lung lobe; ; cerebellar vermis; ; lobe of cerebellum; ; ventromedial nucleus; ; lateral geniculate nucleus; ; aortic valve;
	More reference expression data
	n/a
Gene ontology
Molecular function	phosphoprotein phosphatase activity; phosphatase activity; cadherin binding; protein binding; identical protein binding; protein tyrosine phosphatase activity; transmembrane receptor protein tyrosine phosphatase activity; hydrolase activity;
Cellular component	cytoplasm; integral component of membrane; membrane; cell-cell junction; integral component of plasma membrane; perinuclear region of cytoplasm; lamellipodium; plasma membrane;
Biological process	dephosphorylation; retina layer formation; protein dephosphorylation; negative regulation of endothelial cell migration; negative regulation of endothelial cell proliferation; cell adhesion; negative regulation of angiogenesis; neuron projection development; signal transduction; homophilic cell adhesion via plasma membrane adhesion molecules; retinal ganglion cell axon guidance; peptidyl-tyrosine dephosphorylation;
	Sources:Amigo / QuickGO
Orthologs
	5797
	19274
	ENSG00000173482
	ENSMUSG00000033278
	P28827
	P28828
NM_001105244; NM_002845; NM_001378142; NM_001378143; NM_001378144;
	NM_001378145; NM_001378146; NM_001378147
	NM_008984; NM_001357625
NP_001098714; NP_002836; NP_001365071; NP_001365072; NP_001365073;
	NP_001365074; NP_001365075; NP_001365076
	NP_033010; NP_001344554
	Wikidata
View/Edit Human	View/Edit Mouse

Receptor-type tyrosine-protein phosphatase mu is an enzyme that in humans is encoded by the PTPRM gene.